14 Peer-Reviewed Papers

Research Publications

Our team has published 14 peer-reviewed papers across the world's top AI and computational biology venues, including 1 oral presentation at AAAI-26 in Singapore.

Featured Publication

P7C3-A20 Reverses Alzheimer's Pathology in 5xFAD Mice

Cell Reports Medicine — DOI: 10.1016/j.xcrm.2025.102535

Reversed amyloid plaque accumulation, resolved tau tangles, repaired blood-brain barrier, and restored cognitive function in the most aggressive Alzheimer's mouse model. This landmark paper demonstrates the multi-target therapeutic potential of NAD+ pathway activation via P7C3-A20.

Published January 2026
AAAI-26 Singapore

Conference Presentations

1 oral presentation, 3 poster sessions, and 1 workshop at the 40th AAAI Conference on Artificial Intelligence in Singapore.

David Scott Lewis presenting at AAAI-26 Singapore David Scott Lewis at AAAI-26 Singapore
Oral AAAI-26 Drug Discovery

The Algorithmic Alchemist: Bayesian Optimization Meets Generative AI for Accelerated Drug Discovery

David Scott Lewis, Enrique Zueco, et al.
Poster AAAI-26 Drug Discovery

Cross-Domain Transfer of Causal Discovery: From Molecular Graphs to Financial Networks

David Scott Lewis, Enrique Zueco, et al.
Poster AAAI-26 Drug Discovery

BindCraft-AIXC: Structure-Aware Molecular Generation with Protein Binding Constraints

David Scott Lewis, Enrique Zueco, et al.
Poster AAAI-26

Self-Falsification in Multi-Agent Research Pipelines: A Popperian Framework

David Scott Lewis, Enrique Zueco, et al.
Workshop AAAI-26 Drug Discovery

AI-Scientist v2: 3,000x Acceleration of Experimental Design through Autonomous Hypothesis Generation

David Scott Lewis, Enrique Zueco, et al.
2025 Publications

Conference & Workshop Papers

Peer-reviewed publications across NeurIPS, ICML, ICLR, ISMB, IEEE, and leading AI symposia.

Poster NeurIPS 2025 Drug Discovery

AI for Drug Discovery (AI4D3): Causal Structure Learning in Protein Interaction Networks

David Scott Lewis, Enrique Zueco, et al.
Invited ELLIS 2025

Verified Autonomous Pipelines: Self-Falsification for Trustworthy AI-Driven Research

David Scott Lewis, Enrique Zueco, et al.
Invited Stanford HAI 2025 Drug Discovery

Domain-Agnostic Causal Discovery: A Unified Framework for Scientific Hypothesis Testing

David Scott Lewis, Enrique Zueco, et al.
Poster CIKM 2025

Physics-Informed Verification Surrogates for Autonomous Materials Discovery

David Scott Lewis, Enrique Zueco, et al.
Poster AAMAS 2025

Polyculture vs. Monoculture: Diversity Metrics for Multi-Agent Verification Systems

David Scott Lewis, Enrique Zueco, et al.
Poster ISMB 2025 Drug Discovery

Causal Protein Interaction Networks for Target Identification: A STRING v12.0 Case Study

David Scott Lewis, Enrique Zueco, et al.
Workshop NeurIPS Workshop 2025

Echo Chamber Detection in LLM-Based Research Agents: Metrics and Mitigation

David Scott Lewis, Enrique Zueco, et al.
Workshop ICML Workshop 2025 Drug Discovery

Diffusion Models for Multi-Objective Molecular and Materials Design

David Scott Lewis, Enrique Zueco, et al.
Workshop ICLR Workshop 2025

Benchmarking Autonomous Scientific Discovery: The AIXC Evaluation Suite

David Scott Lewis, Enrique Zueco, et al.
14
Papers
10
Venues
1
Oral Presentations
8
Drug Discovery Papers

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